Nathan Cole Nathan Cole

Cortexa Weekly— February 12 2026

This month marks a meaningful inflection point as Phase 1b and Phase 2 of our six-phase validation roadmap move forward with our CRO partner in Scotland. These studies represent a critical step in strengthening the mechanistic foundation of our proprietary approach and advancing confidence in our biological target.

Read More
Nathan Cole Nathan Cole

Help Us Push ALS Research Forward

In case you missed it, Ahwatukee Foothills News recently featured the story of Cortexa Therapeutics’ founder in an article titled ā€œAhwatukee man fights for his life.ā€ You can read the full feature here.

Today, that fight continues in the lab. I’m working to raise $15,000 to fund the next phase of research at Cortexa Therapeutics, where we are developing a first-of-its-kind ALS treatment targeting calcium-permeable receptors, a mechanism that may finally address one of the root drivers of ALS progression.

These funds will go directly toward critical in-vitro experiments, including testing newly synthesized compounds, expanding motor neuron models, and validating the calcium-dysregulation pathway that could fundamentally change how ALS is treated.

100% of donations go straight to the research.

Read More
Nathan Cole Nathan Cole

Cortexa Weekly— October 7th 2025

It’s been a little while since my last update, and I want to begin by thanking you for your patience. During this time, our team has been hard at work advancing our research — and I’m thrilled to share that we’ve officially launched our Phase 1 studies with our CRO partner, Concept Life Sciences in Edinburgh, Scotland.

Read More
Nathan Cole Nathan Cole

Cortexa Weekly—April 30

This week’s focus: fiscal sponsorship, neurotoxicity, and how your support can help rewrite the future of ALS treatment.

Read More
Nathan Cole Nathan Cole

Cortexa Weekly—April 21

Cortexa is filing a provisional patent and incorporating as a C-Corp, marking major milestones in our mission to fast-track

Read More
Nathan Cole Nathan Cole

Cortexa Weekly—April 15

Cortexa Therapeutics shares major updates: a CNS-focused medicinal chemist joins the team, business development gains…

Read More
Nathan Cole Nathan Cole

Cortexa Weekly—April 2

Neuroscience insights, startup updates, and what I’m thinking about this week. We’re moving fast. This week, we’ve been…

Read More
Nathan Cole Nathan Cole

From Diagnosis to Discovery

From Diagnosis to Discovery: Nathan Cole’s Fight Against ALS with Cortexa Therapeutics. With a mission grounded in urgency,…

Read More